Sports Performance
Validating Sports Performance Products at Vivaltes
At Vivaltes, we use C. elegans and cell-based assays to assess sports performance products efficiently. Our ethical models screen compounds for endurance, muscle function, recovery, and metabolism. With C. elegans mutants, we examine exercise-related pathways, fatigue resistance, and energy metabolism. To strengthen health claims, we integrate metabolomics and RNA sequencing (RNA-seq).
Endurance & Energy Metabolism
We use automated video tracking to investigate endurance effects in C. elegans by monitoring movement patterns and locomotion.
C. elegans models assess mitochondrial function, ATP production, and fat-to-energy conversion. Automated movement tracking helps evaluate stamina, oxidative stress resistance, and metabolic efficiency, offering insights for endurance-enhancing products.
Muscle Function & Strength
Visualisation and monitoring of mitochondrial dynamics in C. elegans muscle cells helps us to study muscle function and health.
Visualisation and monitoring of mitochondrial dynamics in C. elegans muscle cells helps us to study muscle function and health.
Visualising GFP expression in muscles filaments provides insights into muscle structure and function.
Visualising GFP expression in muscles filaments provides insights into muscle structure and function.
C. elegans shares key muscle characteristics with humans, making it ideal for testing muscle strength, protein homeostasis, and neuromuscular coordination. Automated locomotion tracking and sarcomere integrity assays precisely measure muscle function and interventions supporting muscle health.
Recovery & Stress Resilience
Visualising oxidative stress responses in C. elegans is possible with GFP reporter strains.
Post-exercise recovery is vital for performance. C. elegans assays assess oxidative stress, inflammation, and proteostasis to determine how compounds promote cellular repair and resilience. Genetic models reveal stress adaptation pathways, supporting faster recovery and reduced fatigue.
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